abstract：BACKGROUND:Due to technical requirements and cost, hemodiafiltration (HDF) is not widely used in pediatrics. We have been using online HDF (oHDF) since 2009 and we observed low parathyroid hormone (PTH) levels despite the accurate management of CKD-MBD. METHODS:We reviewed the medical charts and parameters of mineral ...

journal_title：Nephrologie & therapeutique

authors： Pérouse de Montclos T,Ranchin B,Leclerc AL,Bertholet-Thomas A,Belot A,Cochat P,Bacchetta J

更新日期：2014-02-01 00:00:00

abstract：:Since the introduction of the first magnesium pharmaceutical specialty in 1928, multiple medical indications were attributed to magnesium supplementation, despite rigorous scientific researches, leading to a very confuse therapeutic chapter. Real hypomagnesemia, acute or chronic, is rare, however oral magnesium drugs ...

journal_title：Nephrologie & therapeutique

authors： Penquerc'h M,Picot D,Vigneau C

更新日期：2014-02-01 00:00:00

abstract：:Continuous renal replacement therapy (CRRT) with a high cutoff (HCO) membrane is proposed for septic shock as a blood purification technique. The aim of this therapy is to modulate the immune response through the increase of the clearances of the inflammatory mediators as compared to standard CRRT. The use of HCO memb...

journal_title：Nephrologie & therapeutique

authors： Madelaine T,Page M,Prothet J,Ber CÉ,Crozon J,Allaouchiche B,Rimmelé T

更新日期：2013-12-01 00:00:00

abstract：:The optimal method to assess the adequacy of peritoneal dialysis therapies is controversial. Today, the adequacy must not be considered as a number or a concept assessed only by two parameters (total KT/V urea and total solute clearance) but defined by many more items. In the absence of data, based on theoretical cons...

journal_title：Nephrologie & therapeutique

authors： Issad B,Durand PY,Siohan P,Goffin E,Cridlig J,Jean G,Ryckelynck JP,Commission de dialyse de la Société de néphrologie.,Arkouche W,Bourdenx JP,Cridlig J,Dallaporta B,Fessy H,Fischbach M,Giaime P,Goffin E,Issad B,Jean G,

更新日期：2013-11-01 00:00:00

abstract：:Cohort studies, mainly US, show that vitamin D deficiency is more common in African-American population. Social and environmental factors play a role but the difference in skin color is essential. Despite low 25-hydroxyvitamin D concentrations, a lower risk of fragility or fracture exists in these populations. Vitamin...

journal_title：Nephrologie & therapeutique

authors： Chauveau P,Aparicio M

更新日期：2013-11-01 00:00:00

abstract：:This chapter provides indicators to describe the specificity of End Stage Renal Disease in children in France and to study these patients'outcome and the choices of treatment modalities. In 2011, the incidence and the prevalence of ESRD among patients under 20 years old remained stable at 8 and 53 pmp respectively. Th...

journal_title：Nephrologie & therapeutique

authors： Harambat J,Hogan J,Macher MA,Couchoud C,registre du REIN.

更新日期：2013-09-01 00:00:00

abstract：:For a few years, new targeted therapies have been used for metastatic cancers, targeting VEGF and its receptors and improving patients' survival for metastatic carcinoma (kidney, GIST, breast, colorectal). The objective of these treatments is to block either circulating VEGF (bevacizumab; VEGF-Trap), or tyrosine kinas...

journal_title：Nephrologie & therapeutique

authors： Vigneau C,Rioux-Leclercq N

更新日期：2013-06-01 00:00:00

abstract：:Recently, several meta-analysis suggested an increased risk of cancers linked to the use of antagonists of angiotensin-2 receptors or inhibitors of angiotensinogen converting enzyme. The results of epidemiological studies are conflicting. Meta-analysis as well as retrospective studies are not reliable and biased, sinc...

journal_title：Nephrologie & therapeutique

authors： Dolley-Hitze T,Verhoest G,Jouan F,Le Pogamp P,Arlot-Bonnemains Y,Oger E,Belaud-Rotureau MA,Rioux-Leclercq N,Vigneau C

更新日期：2013-04-01 00:00:00

abstract：:Mitochondrial disorders are genetic defects of oxidative phosphorylation. Oxidative phosphorylation takes place in the mitochondrial inner membrane and consists of the oxidation of fuel molecules by oxygen and the concomitant energy transduction into ATP. The mitochondrial respiratory chain is a complex metabolic path...

journal_title：Nephrologie & therapeutique

authors： Niaudet P

更新日期：2013-04-01 00:00:00

abstract：:In France, the incidence of dialysis patients is increasing in people over 75 years and represents 40% of incident patients. In these elderly patients with many comorbidities, the benefit of dialysis in terms of survival and quality of life remains controversial. Using data from REIN, determinants of early mortality w...

journal_title：Nephrologie & therapeutique

authors： Moranne O,Couchoud C,Kolko-Labadens A,Allot V,Fafin C,Vigneau C

更新日期：2012-12-01 00:00:00

abstract：:The recent history of French and Brazilian medicine goes back to the first decades of the xixth century. As regards nephrology, the first links were established starting in the 1950s of the xxth century. Over the past 60 years, the scientific production of the Franco-Brazilian school of nephrology totalized more than ...

journal_title：Nephrologie & therapeutique

authors： de Oliveira RB,Cruz J,Drüeke TB,Massy Z

更新日期：2012-12-01 00:00:00

abstract：:Extracellular content in magnesium represents about 1% of total body content, of which plasma magnesium is thus a poor reflect. Hypomagnesaemia is defined by a value lesser than 0.65mmol/L. Its incidence in hospitalized patients ranges between 10 and 15%. Identification of the physiopathology of hypomagnesaemia relies...

journal_title：Nephrologie & therapeutique

authors： Blanchard A,Vargas-Poussou R

更新日期：2012-11-01 00:00:00

abstract：:Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...

journal_title：Nephrologie & therapeutique

authors： Ranchin B,Demede D,Javouhey E,Basmaison O,Cejka JC,Bertholet-Thomas A,Hameury F,Martin X,Cochat P,Badet L

更新日期：2011-12-01 00:00:00

abstract：:Malignancies and opportunistic infections are frequently observed after solid-organ transplantation. Their occurrence strongly affects recipient survival. We report the case of a 29-year-old Tunisian kidney-recipient who was diagnosed simultaneously with post-transplant lymphoproliferative disease (PTLD) and visceral ...

journal_title：Nephrologie & therapeutique

authors： Bacha MM,Abderrahim E,Ounissi M,Chaouech D,Cherif M,Turki S,Rajhi H,Znaidi N,Bahloul A,Trabelsi S,Khaled S,Ben Abdallah T,Ben Maïz H,Kheder A

更新日期：2011-11-01 00:00:00

abstract：:In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...

journal_title：Nephrologie & therapeutique

authors：

更新日期：2011-09-01 00:00:00

abstract：:Primary hyperoxalurias are rare recessive inherited inborn errors of glyoxylate metabolism. They are responsible for progressive renal involvement, which further lead to systemic oxalate deposition, which can even occur in infants. Primary hyperoxaluria type 1 is the most common form in Europe and is due to alanine-gl...

journal_title：Nephrologie & therapeutique

authors： Cochat P,Fargue S,Bacchetta J,Bertholet-Thomas A,Sabot JF,Harambat J

更新日期：2011-07-01 00:00:00

abstract：:The renal transplantation is nowadays the reference treatment of ESRD. Living donor kidney transplantation is less often performed in France than in other countries. Nevertheless, numerous French and international surveys have evidenced that it provides the recipients a longer life expectancy and a better quality of l...

journal_title：Nephrologie & therapeutique

authors： Briançon S,Germain L,Baudelot C,Bannay A,Virion JM,Thuong M

更新日期：2011-07-01 00:00:00

abstract：:Definition and classification of acute renal failure evolved in recent years. The acronym "Acute Kidney Injury" replaces "Acute Renal Failure". The RIFLE classification spreads the AKI in three degrees of severity, and two degrees of disease duration. The group Acute Kidney Injury Network refines this classification i...

journal_title：Nephrologie & therapeutique

authors： Moonen M,Fraipont V,Radermacher L,Masset C,Firre E,Warling X

更新日期：2011-06-01 00:00:00

abstract：:Substituting bicarbonate by acetate in dialysis fluids has been proposed for avoiding precipitation of calcium and magnesium carbonates. However, acetate hemodialysis has been abandoned because of deleterious effects of acetate. Conventional bicarbonate hemodialysis is not totally acetate-free, because 3 to 7 mEq/l of...

journal_title：Nephrologie & therapeutique

authors： Petitclerc T,Diab R,Le Roy F,Mercadal L,Hmida J

更新日期：2011-04-01 00:00:00

abstract：:Calcium and phosphate play a key role in bone mineralization but have also many other physiological functions. The control of serum phosphate concentration is mandatory to avoid the occurrence of severe metabolic disorders, but is less tightly regulated than serum ionized calcium concentration, which is maintained in ...

journal_title：Nephrologie & therapeutique

authors： Courbebaisse M,Souberbielle JC

更新日期：2011-04-01 00:00:00

abstract：:The management of lupus nephritis remains a clinical problem in children as in adults. Corticosteroids, cyclophosphamide and azathioprine have been used with satisfactory response, but the most important problems are their potential toxicities. Therefore, we evaluate the use of mycophenolate mofetil (MMF) as a new age...

journal_title：Nephrologie & therapeutique

authors： Gargah T,Goucha-Louzir R,Lakhoua MR

更新日期：2010-12-01 00:00:00

abstract：:IgA nephropathy is the primitive glomerulonephritis the most frequently encountered worldwide. In about one case out of three, it is responsible for the progression from progressive renal failure to end-stage renal failure. The pathophysiological mechanisms of this disease which is mediated by immune complexes remain ...

journal_title：Nephrologie & therapeutique

authors： Pillebout E,Nochy D

更新日期：2010-11-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a worldwide public health problem. Little is known about its burden in Africa. This paper reviews the knowledge of CKD in Kinshasa, summarizing four studies undertaken in the general population and traditional health system of Kinshasa. CKD was defined by either kidney damage (proteinur...

journal_title：Nephrologie & therapeutique

authors： Sumaili EK,Krzesinski JM,Cohen EP,Nseka NM

更新日期：2010-07-01 00:00:00

abstract：:Surgical removal of a hemodialysis access after thrombosis is generally not performed as it remains clinically well tolerated. However, it may be the source of distal embolization. We report the case of a 43-year-old patient, kidney recipient, who presented with digital ischemia of the right hand. He had a forearm art...

journal_title：Nephrologie & therapeutique

authors： Journet J,Bui HT,Capdevila C,Lavaud S,Hadj Henni A,Clément C,Rieu P,Long A

更新日期：2010-04-01 00:00:00

abstract：:Hepatitis E virus (HEV) causes epidemics of acute hepatitis in developing countries, and also appears to be an emerging agent in industrialized countries. HEV infection is transmitted via the fecal-oral route, and may be a zoonosis in industrialized countries. HEV infection was thought to be responsible for acute hepa...

journal_title：Nephrologie & therapeutique

authors： Kamar N,Abravanel F,Mansuy JM,Peron JM,Izopet J,Rostaing L

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:The treatment of secondary hyperparathyroidism (SHPT) in dialysis patients has changed with the introduction of cinacalcet (CC), which represents a medical alternative to surgical parathyroidectomy (PTX). The aim of our study is to prospectively assess the tolerance and efficacy of CC in patients, treated ...

journal_title：Nephrologie & therapeutique

authors： Jean G,Vanel T,Terrat JC,Hurot JM,Lorriaux C,Mayor B,Deleaval P,Vovan C,Chazot C

更新日期：2010-04-01 00:00:00

abstract：:Proliferation signal inhibitors (PSI) have been used in France for kidney transplants for some ten years. They provide a certain number of long-term benefits for kidney function in transplant patients due to their anti-proliferation and anti-tumour properties and absence of nephrotoxicity. Their use has been evaluated...

journal_title：Nephrologie & therapeutique

authors： Ladrière M

更新日期：2009-12-01 00:00:00

abstract：:A patient is admitted in hospital to explore a nephrotic proteinuria associated with milky urine. This is explained by a chyluria (presence of lymphatic fluid in the urines), which is due to a pyelolymphatic fistula probably linked to a lymphatic filariasis. Usually, the diagnosis of chyluria can be confirmed by the p...

journal_title：Nephrologie & therapeutique

authors： Poitou C,Kheder-Elfekih R,Djebbar M,Perreira P,Deray G,Izzedine H

更新日期：2009-12-01 00:00:00

abstract：:The dramatic occurrence, during haemodialysis sessions, of hemodynamic and cerebral symptoms in a 53-year-old haemodialysed woman with a history of aortocoronary bypass leads to discovery and treatment by percutaneous angioplasty and stenting of a significant stenosis of proximal subclavian artery, ipsilateral to the ...

journal_title：Nephrologie & therapeutique

authors： Cluzel P,Chabrot P,Citron B,Gazuy N,Cassagnes L,Boyer L,Lipiecki J,Bonniol C

更新日期：2009-12-01 00:00:00

abstract：:Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...

journal_title：Nephrologie & therapeutique

authors： Kunz K,Hannedouche T

更新日期：2009-07-01 00:00:00

abstract：:We report seven cases of patients treated with fluindione, who presented with acute renal failure, associated with clinical features of allergy: poor status, fever, dyspnea, lymphadenopathy and erythroderma. All patients had elevated eosinophil counts. Renal biopsy disclosed in all cases a tubulo-interstitial nephriti...

journal_title：Nephrologie & therapeutique

authors： Reynaud F,Giraud P,Cisterne JM,Verdier D,Kouchakipour Z,Hermelin A,Modesto-Segonds A,Bagheri H,Pourrat J

更新日期：2009-07-01 00:00:00

abstract：:Clinical nephrology in the european french-speaking countries made great strides just after the 2nd World War. The "Société de Pathologie Rénale" was founded and assembles French, Belgian and Swiss nephrologists. The first studies were physiopathological and bore on acute uremia and the associated hydromineral disorde...

journal_title：Nephrologie & therapeutique

authors： Richet G

更新日期：2009-06-01 00:00:00

abstract：:Conventional peritoneal dialysis solutions are mostly bioincompatible in relationship with a low pH, a high glucose and glucose degradation products (GDP) concentrations inducing anatomical and functional peritoneal membrane alterations. Use of icodextrin solution instead of glucose hypertonic solution preserves perit...

journal_title：Nephrologie & therapeutique

authors： Ryckelynck JP,Lobbedez T,Ficheux M,Chatelet V,Thuillier-Lecouf A,Henri P,Hurault de Ligny B

更新日期：2009-06-01 00:00:00

abstract：UNLABELLED:Ethylene glycol is present predominantly in antifreeze,and in industrial solvents. Accidental ingestion of ethylene glycol is relatively rare, but may be potentially lethal. It results in a depression of the central nervous system, a severe metabolic acidosis and an acute renal failure by tubular precipitati...

journal_title：Nephrologie & therapeutique

authors： Bouattar T,Madani N,Hamzaoui H,Alhamany Z,El Quessar A,Benamar L,Rhou H,Abouqual R,Zeggwagh A,Bayahia R,Ouzeddoun N

更新日期：2009-06-01 00:00:00

abstract：:The predominant cause of hereditary renal amyloidosis is a mutation of the fibrinogen Aalpha chain (AFib), the most common being the E526V mutation. The evolution towards terminal renal insufficiency is constant and raises the question of renal transplantation and the risk of recurrence. We describe the case of a Port...

journal_title：Nephrologie & therapeutique

authors： Delabre JP,Pageaux GP,Le Quellec A,Raynaud P,Grateau G,Mourad G

更新日期：2009-04-01 00:00:00

abstract：:In reference to psychopathology, the authors highlight several indicators of the aging dialysed patient's psychological functioning. The aim of this work is to extract some indicators in order to help these patients to experience a pleasant aging, in spite of a difficult disease state, constraining care and the presen...

journal_title：Nephrologie & therapeutique

authors： Cupa D,Riazuelo H,Causeret C,Gourdon ML,Pirlot G

更新日期：2009-04-01 00:00:00

abstract：:The potential neurotoxicity of betalactam antibiotics are well-known and is frequently associated with drug accumulation in patients with renal failure since these antibiotics are eliminated mostly by kidneys. The regional center of pharmacovigilance of Amiens has collected since 10 years, 20 notifications of neurotox...

journal_title：Nephrologie & therapeutique

authors： Lemaire-Hurtel AS,Gras-Champel V,Hary L,Masmoudi K,Massy Z,Andréjak M

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Emphysematous pyelonephritis is a rare and severe form of acute pyelonephritis. It is defined as the presence of gas-producing bacteria in the kidney and in peri-nepheretic areas. We report a case of emphysematous pyelonephritis on a single kidney associated with urolithiasis. OBSERVATION:A 44-year-old wo...

journal_title：Nephrologie & therapeutique

authors： Aatif T,Asseraji M,Chafiki J,Maoujoud O,Akhmouch I,Hassani M,Ameur A,El Aalam M,Oualim Z

更新日期：2009-02-01 00:00:00

abstract：:The understanding of water traffic through biological membranes has tremendously progressed with the discovery of the aquaporins. Aquaporins water channels inserted in lipid bilayer drive specific, regulated, water flux under osmotic gradient. Some of them, the aquaglycéroporines, are permeated by urea, glycerol and o...

journal_title：Nephrologie & therapeutique

authors： Pietrement C

更新日期：2008-12-01 00:00:00

abstract：:The overall risk of cancer in the kidney transplant patient is three to five times higher than the risk in the general population, and the risk of cutaneous epitheliomas, the most frequent, is multiplied by 100. There are many causes of posttransplantation cancer involving modifications in the immunosurveillance of ne...

journal_title：Nephrologie & therapeutique

authors： Moal MC

更新日期：2008-10-01 00:00:00